Psychosocial factors associated with the uptake of contralateral prophylactic mastectomy among BRCA1/2 mutation noncarriers with newly diagnosed breast cancer Academic Article uri icon


MeSH Major

  • Carcinoma, Squamous Cell
  • Health Knowledge, Attitudes, Practice
  • Oropharyngeal Neoplasms
  • Papillomavirus Infections
  • Quality of Life


  • A sizeable minority of BRCA1/2 mutation noncarriers choose to undergo CPM after learning their mutation status through pre-surgical genetic testing. BRCA1/2 mutation noncarriers' cognitive perceptions and social influences appear to be important in shaping their decisions regarding CPM. This work highlights the importance of several psychosocial factors in influencing patients' surgical decisions. Future research is needed that examines the formation of BRCA1/2 mutation noncarriers' beliefs regarding their disease and available treatment options, and that characterizes the physician-patient communication that occurs in this complex decision-making context.

publication date

  • February 2017



  • Academic Article



  • eng

PubMed Central ID

  • PMC5329117

Digital Object Identifier (DOI)

  • 10.1007/s10549-017-4123-x

PubMed ID

  • 28150129

Additional Document Info

start page

  • 1

end page

  • 10