Autophagy-dependent danger signaling and adaptive immunity to poorly immunogenic tumors Academic Article uri icon

Overview

MeSH Major

  • Autophagy
  • Biological Assay

abstract

  • Recent data suggest that autophagy does not influence spontaneous and therapy-elicited tumor infiltration by immune cells in murine models of melanoma and breast carcinoma. These findings, which have been obtained in the absence of a therapeutically relevant anticancer immune response, indicate that the intrinsically low immunogenicity of some tumors cannot be compensated for by increased danger signaling.

publication date

  • January 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5351581

Digital Object Identifier (DOI)

  • 10.18632/oncotarget.13892

PubMed ID

  • 27974686

Additional Document Info

start page

  • 5686

end page

  • 5691

volume

  • 8

number

  • 4