In situ reprogramming to transdifferentiate fibroblasts into cardiomyocytes using adenoviral vectors: Implications for clinical myocardial regeneration Academic Article uri icon

Overview

MeSH Major

  • Adenoviridae
  • Choice Behavior
  • Cocaine
  • Self Administration
  • Vaccines

abstract

  • Ad vectors are at least as effective as lentiviral vectors in inducing cardiac fibroblast transdifferentiation into induced cardiomyocyte-like cells and improving cardiac function in postinfarct rat hearts. Short-term expression Ad┬ávectors may represent an important means to induce cardiac cellular reprogramming in humans.

publication date

  • February 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5297447

Digital Object Identifier (DOI)

  • 10.1016/j.jtcvs.2016.09.041

PubMed ID

  • 27773576

Additional Document Info

start page

  • 329

end page

  • 339.e3

volume

  • 153

number

  • 2