Surgery of the head and neck in patient with Kniest dysplasia: Is wound healing an issue? Academic Article uri icon

Overview

MeSH Major

  • Cleft Palate
  • Cochlear Implantation
  • Collagen Diseases
  • Dwarfism
  • Face
  • Hyaline Membrane Disease
  • Mandibular Advancement
  • Orthognathic Surgical Procedures
  • Osteochondrodysplasias
  • Otorhinolaryngologic Surgical Procedures
  • Wound Healing

abstract

  • © 2016 Elsevier Ireland LtdKniest dysplasia is a type II collagen disorder that arises from a genetic mutation of the COL2A1 gene that results in short stature, midface anomalies, tracheomalacia, and hearing loss. Disruption of the normal collagen pathway can lead to many changes given its critical role in the body, and can cause complications with respect to wound healing. We present a case in which a patient with Kniest dysplasia successfully underwent multiple procedures in the head and neck region including cochlear implantation, mandibular distraction, palatoplasty, and laryngotracheal reconstruction. All procedures did not have any associated complications with respect to wound healing, indicating that surgery in this population can take place as indicated and surgery should not be contraindicated or delayed.

publication date

  • February 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.ijporl.2016.12.025

PubMed ID

  • 28109507

Additional Document Info

start page

  • 97

end page

  • 99

volume

  • 93