Lymph node transplantation decreases swelling and restores immune responses in a transgenic model of lymphedema Academic Article uri icon

Overview

MeSH Major

  • Lymph Nodes
  • Lymphedema

abstract

  • LNT decreases pathological changes of lymphedema and was shown to potently induce lymphangiogenesis. Lymphatic vessels induced by LNT were abnormal in appearance, but were functional and able to transport antigen-presenting cells. Animals treated with LNT have an increased ability to mount T cell-mediated immune responses when sensitized to antigens in the affected hindlimb.

publication date

  • December 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5152898

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0168259

PubMed ID

  • 27942023

Additional Document Info

start page

  • e0168259

volume

  • 11

number

  • 12