Neoadjuvant therapy for rectal cancer affects lymph node yield and status without clear implications on outcome: The case for eliminating a metric and using preoperative staging to guide therapy Academic Article Article uri icon

Overview

MeSH Major

  • Central Nervous System Neoplasms
  • Drug Delivery Systems
  • Molecular Imaging
  • Molecular Targeted Therapy

abstract

  • This analysis reiterates that nodal yield in rectal cancer is multifactorial, with neoadjuvant therapy being a significant factor. Node yield and status were not significant predictors of overall survival. A nodal metric may not be clinically relevant in the era of neoadjuvant therapy, and guidelines for perioperative therapy may need reconsideration.

publication date

  • December 2016

Research

keywords

  • Academic Article

Identity

PubMed ID

  • 27956537

Additional Document Info

start page

  • 1528

end page

  • 1534

volume

  • 14

number

  • 12