The effects of hematopoietic stem cell transplant on splenic extramedullary hematopoiesis in patients with myeloproliferative neoplasm-associated myelofibrosis Academic Article uri icon

Overview

MeSH Major

  • Bone Marrow Neoplasms
  • Hematopoiesis, Extramedullary
  • Hematopoietic Stem Cell Transplantation
  • Primary Myelofibrosis
  • Spleen

abstract

  • HSCT reduces/abrogates splenic EMH and is associated with an increased number of Gamna-Gandy bodies, which may suggest vascular damage. The lack of stromal changes in spleens removed shortly after transplant is in line with similar observations in the BM, where a longer interval is often necessary for resolution of fibrosis.

publication date

  • February 17, 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.hemonc.2016.07.002

PubMed ID

  • 27521149

Additional Document Info

start page

  • 96

end page

  • 104