Interobserver agreement in the cytologic grading of atypia in neoplastic pancreatic mucinous cysts with the 2-tiered approach Academic Article uri icon


MeSH Major

  • Adenocarcinoma, Mucinous
  • Pancreatic Cyst
  • Pancreatic Neoplasms


  • This study shows that the cytologic recognition of HG dysplasia or worse as HG atypia in pancreatic mucinous cysts has a good degree of interobserver reproducibility among cytopathologists. In contrast, a problematic area with a lack of agreement appears to be the cytologic recognition of LG and IG dysplasia as LG atypia. Additional studies with the development of reproducible criteria and educational tools may help with this challenging distinction. Cancer Cytopathol 2016. © 2016 American Cancer Society.

publication date

  • January 2016



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncy.21767

PubMed ID

  • 27525382

Additional Document Info