Structural explanation of poor prognosis of amyotrophic lateral sclerosis in the non-demented state Academic Article uri icon

Overview

MeSH Major

  • Amyotrophic Lateral Sclerosis
  • Atrophy
  • Gray Matter
  • Motor Cortex

abstract

  • These findings also support the hypothesis that ALS pathogenesis has a dual focality of onset (cortex and anterior horn) with contiguous spread outwards. Additionally, neuropsychological features may be an important predictor of progression and survival rates in ALS.

publication date

  • January 2017

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5436047

Digital Object Identifier (DOI)

  • 10.1111/ene.13163

PubMed ID

  • 27753163

Additional Document Info

start page

  • 122

end page

  • 129

volume

  • 24

number

  • 1