Phase 2 study of concurrent radiotherapy and temozolomide followed by temozolomide and lomustine in the treatment of children with high-grade glioma: A report of the Children's Oncology Group ACNS0423 study Academic Article uri icon

Overview

MeSH Major

  • Brain Neoplasms
  • Chemoradiotherapy
  • Glioma

abstract

  • The addition of lomustine to temozolomide as adjuvant therapy in ACNS0423 was associated with significantly improved outcome compared with the preceding COG ACNS0126 HGG study in which participants received temozolomide alone.

publication date

  • October 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5035517

Digital Object Identifier (DOI)

  • 10.1093/neuonc/now038

PubMed ID

  • 27006176

Additional Document Info

start page

  • 1442

end page

  • 50

volume

  • 18

number

  • 10