The transcriptional signature of active tuberculosis reflects symptom status in extra-pulmonary and pulmonary tuberculosis Academic Article uri icon

Overview

MeSH Major

  • Transcriptome
  • Tuberculosis
  • Tuberculosis, Pulmonary

abstract

  • The transcriptional signature in extra-pulmonary TB demonstrated heterogeneity of gene expression reflective of symptom status, while the signature of pulmonary TB was distinct, based on a higher proportion of symptomatic individuals. These findings are of importance for the rational design and implementation of mRNA based TB diagnostics.

publication date

  • October 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5051928

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0162220

PubMed ID

  • 27706152

Additional Document Info

start page

  • e0162220

volume

  • 11

number

  • 10