Comparing Presenting Clinical Features in 48 Children With Microscopic Polyangiitis to 183 Children Who Have Granulomatosis With Polyangiitis (Wegener's): An ARChiVe Cohort Study Academic Article uri icon

Overview

MeSH Major

  • Granulomatosis with Polyangiitis
  • Hemorrhage
  • Kidney Failure, Chronic
  • Lung Diseases
  • Microscopic Polyangiitis
  • Nephrotic Syndrome
  • Respiratory Insufficiency

abstract

  • Younger age at disease onset and, perhaps, both gastrointestinal manifestations and more severe kidney disease seem to characterize the clinical profile in children with MPA compared to those with GPA. Delay in diagnosis suggests that recognition of these systemic vasculitides is suboptimal. Compared with adults, initial treatment regimens in children were comparable, but the complete reversal of female-to-male disease prevalence ratios is a provocative finding.

authors

publication date

  • October 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/art.39729

PubMed ID

  • 27111558

Additional Document Info

start page

  • 2514

end page

  • 26

volume

  • 68

number

  • 10