Genomic Characterization of Upper Tract Urothelial Carcinoma Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Transitional Cell
  • Genomics
  • Kidney Neoplasms
  • Mutation
  • Ureteral Neoplasms
  • Urinary Bladder Neoplasms

abstract

  • Comparison of next-generation sequencing of upper tract urothelial carcinoma (UTUC) with urothelial bladder cancer identified that similar mutations were present in both cancer types but at different frequencies, indicating a potential need for unique management strategies. UTUC tumors were found to have a high rate of mutations that could be targeted with novel therapies.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4675454

Digital Object Identifier (DOI)

  • 10.1016/j.eururo.2015.07.039

PubMed ID

  • 26278805

Additional Document Info

start page

  • 970

end page

  • 7

volume

  • 68

number

  • 6