Genomic Characterization of Upper Tract Urothelial Carcinoma
Carcinoma, Transitional Cell
Urinary Bladder Neoplasms
Comparison of next-generation sequencing of upper tract urothelial carcinoma (UTUC) with urothelial bladder cancer identified that similar mutations were present in both cancer types but at different frequencies, indicating a potential need for unique management strategies. UTUC tumors were found to have a high rate of mutations that could be targeted with novel therapies.