Sentinel lymph nodes for breast carcinoma: A paradigm shift Review uri icon


MeSH Major

  • Breast
  • Breast Neoplasms
  • Sentinel Lymph Node
  • Sentinel Lymph Node Biopsy


  • -The main goal of sentinel lymph node examination should be to detect all macrometastases (>2 mm). Grossly sectioning sentinel lymph nodes at 2-mm intervals and evaluation of one hematoxylin-eosin-stained section from each block is the preferred method of pathologic evaluation. Axillary lymph node dissection can be safely omitted in clinically node-negative patients with negative sentinel lymph nodes, as well as in a selected group of patients with limited sentinel lymph node involvement. The pathologic features of the primary carcinoma and its sentinel lymph node metastases contribute to estimate the extent of non-sentinel lymph node involvement. This information is important to decide on further axillary treatment.

publication date

  • August 2016



  • Review



  • eng

PubMed Central ID

  • PMC5027875

Digital Object Identifier (DOI)

  • 10.5858/arpa.2015-0140-RA

PubMed ID

  • 27472237

Additional Document Info

start page

  • 791

end page

  • 8


  • 140


  • 8