Preclinical Pharmacology of CW002: A Nondepolarizing Neuromuscular Blocking Drug of Intermediate Duration, Degraded and Antagonized by L-cysteine: Additional Studies of Safety and Efficacy in the Anesthetized Rhesus Monkey and Cat Academic Article uri icon

Overview

MeSH Major

  • Cysteine
  • Hemodynamics
  • Isoquinolines
  • Lung
  • Neuromuscular Blocking Agents

abstract

  • The data further verify the neuromuscular blocking properties of CW002, including rapid reversal by L-cysteine of 100% NMB under several circumstances. A notable lack of autonomic or circulatory effects provided added proof of safety and efficacy.

publication date

  • July 26, 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1097/ALN.0000000000001254

PubMed ID

  • 27466033

Additional Document Info