Association of interferon regulatory factor-4 polymorphism rs12203592 with divergent melanoma pathways
Interferon Regulatory Factors
Polymorphism, Single Nucleotide
Our findings suggest a role of IRF4 rs12203592 in pathway-specific risk for melanoma development. We hypothesize that IRF4 rs12203592 could underlie in part the bimodal age distribution reported for melanoma and linked to the divergent pathways.