Next-generation sequencing of pulmonary large cell neuroendocrine carcinoma reveals small cell carcinoma-like and non-small cell carcinoma-like subsets Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Non-Small-Cell Lung
  • Lung Neoplasms
  • Mutation
  • Proto-Oncogene Proteins B-raf

abstract

  • LCNEC is a biologically heterogeneous group of tumors, comprising distinct subsets with genomic signatures of SCLC, NSCLC (predominantly adenocarcinoma), and rarely, highly proliferative carcinoids. Recognition of these subsets may inform the classification and management of LCNEC patients. Clin Cancer Res; 22(14); 3618-29. ©2016 AACR.

publication date

  • July 15, 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4995776

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-15-2946

PubMed ID

  • 26960398

Additional Document Info

start page

  • 3618

end page

  • 29

volume

  • 22

number

  • 14