Prognosis of mucosal, uveal, acral, nonacral cutaneous, and unknown primary melanoma from the time of first metastasis Academic Article uri icon


MeSH Major

  • Melanoma
  • Receptor Protein-Tyrosine Kinases
  • Skin Neoplasms


  • Uveal, acral, and mucosal melanoma are assumed to result in a worse prognosis than nonacral cutaneous melanoma or unknown primary melanoma. No studies, however, have been conducted assessing the overall survival of patients with these melanoma subtypes starting at the time of distant metastatic disease. The present study found that patients with uveal, acral, nonacral cutaneous, and unknown primary melanoma have similar overall survival after distant metastases have been diagnosed. These findings provide information for oncologists to reconsider previously held assumptions and appropriately counsel patients. Patients with mucosal melanoma have worse overall survival and are thus a group in need of specific research and advocacy.

publication date

  • July 2016



  • Academic Article



  • eng

PubMed Central ID

  • PMC4943393

Digital Object Identifier (DOI)

  • 10.1634/theoncologist.2015-0522

PubMed ID

  • 27286787

Additional Document Info

start page

  • 848

end page

  • 54


  • 21


  • 7