Evaluating permeability surface-area product as a measure of blood-brain barrier permeability in a murine model Academic Article uri icon

Overview

MeSH Major

  • Brain Edema
  • Perfusion Imaging
  • Subarachnoid Hemorrhage
  • Tomography, X-Ray Computed

abstract

  • Permeability surface-area product is increased in situations with known disruptions of the BBB, as evidenced by immunologic staining of large-vector passage through the BBB and concordance with contrast-enhancement measurements in a murine model. Quantitative permeability surface-area product has potential as an imaging marker of BBB permeability.

publication date

  • July 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4946982

Digital Object Identifier (DOI)

  • 10.3174/ajnr.A4712

PubMed ID

  • 26965465

Additional Document Info

start page

  • 1267

end page

  • 74

volume

  • 37

number

  • 7