Folate receptor a expression level correlates with histologic grade in lung adenocarcinoma Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Folate Receptor 1
  • Lung Neoplasms

abstract

  • -Folate receptor α protein was expressed in the majority of lung adenocarcinomas and a minority of lung squamous cell carcinomas. Folate receptor α protein expression correlated with histologic grade for lung adenocarcinomas, and the greatest difference was observed between grade 1 and grade 3. Our results indicate that poorly differentiated adenocarcinomas or focuses of poor differentiation in a heterogeneous tumor may lack FRA protein expression and be more likely to be resistant to FRA-targeting drugs.

publication date

  • July 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.5858/arpa.2015-0431-OA

PubMed ID

  • 26599808

Additional Document Info

start page

  • 682

end page

  • 5

volume

  • 140

number

  • 7