Prevention of breast cancer by RANKL/RANK blockade Article uri icon

Overview

MeSH Major

  • Autophagy
  • Enzyme Inhibitors
  • Spermidine
  • Stilbenes

abstract

  • Robust genetic evidence in mice and humans indicates that RANK signaling plays a major role in mammary carcinogenesis driven by BRCA1/BRCA2 mutations. These findings may inaugurate a new era of breast cancer prevention, changing the life of millions of women worldwide.

publication date

  • July 2016

Research

keywords

  • Article

Identity

Digital Object Identifier (DOI)

  • 10.1038/cr.2016.79

Additional Document Info

start page

  • 751

end page

  • 2

volume

  • 26

number

  • 7