Change in chemotherapy during concurrent radiation followed by surgery after a suboptimal positron emission tomography response to induction chemotherapy improves outcomes for locally advanced esophageal adenocarcinoma Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Esophageal Neoplasms
  • Induction Chemotherapy
  • Neoadjuvant Therapy
  • Positron-Emission Tomography

abstract

  • A PET scan after induction chemotherapy predicts outcomes for locally advanced esophageal adenocarcinoma patients who undergo chemoradiation and surgery. The median PFS is improved, and trends toward improved OS appear possible in PET nonresponders who change chemotherapy during radiation. The fully accrued Cancer and Leukemia Group B 80803 study (NCT01333033) is evaluating this strategy. Cancer 2016;122:2083-90. © 2016 American Cancer Society.

publication date

  • July 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4911302

Digital Object Identifier (DOI)

  • 10.1002/cncr.30028

PubMed ID

  • 27152857

Additional Document Info

start page

  • 2083

end page

  • 90

volume

  • 122

number

  • 13