Basal cell skin cancer, version 1.2016: Clinical practice guidelines in oncology Article Report uri icon

Overview

MeSH Major

  • Iodine Radioisotopes
  • Practice Guidelines as Topic
  • Radiation Oncology
  • Radiopharmaceuticals
  • Thyroid Neoplasms
  • Thyroidectomy

abstract

  • Basal cell carcinoma (BCC) of the skin is the most common cancer, with a higher incidence than all other malignancies combined. Although it is rare to metastasize, patients with multiple or frequently recurring BCC can suffer substantial comorbidity and be difficult to manage. Assessment of risk is a key element of management needed to inform treatment selection. The overall management of BCC primarily consists of surgical approaches, with radiation therapy as an alternate or adjuvant option. Many superficial therapies for BCC have been explored and continue to be developed, including topicals, cryosurgery, and photodynamic therapy. Two hedgehog pathway inhibitors were recently approved by the FDA for systemic treatment of advanced and metastatic BCC, and others are in development. The NCCN Guidelines for Basal Cell Skin Cancer, published in full herein, include recommendations for selecting among the various surgical approaches based on patient-, lesion-, and disease-specific factors, as well as guidance on when to use radiation therapy, superficial therapies, and hedgehog pathway inhibitors.

authors

publication date

  • May 2016

Research

keywords

  • Report

Identity

PubMed ID

  • 27160235

Additional Document Info

start page

  • 574

end page

  • 97

volume

  • 14

number

  • 5