Management of perioperative tumour necrosis factor α inhibitors in rheumatoid arthritis patients undergoing arthroplasty: A systematic review and meta-analysis Review uri icon

Overview

MeSH Major

  • Arthritis, Rheumatoid
  • Arthroplasty
  • Surgical Wound Infection
  • Tumor Necrosis Factor-alpha

abstract

  • Data from the available literature suggest that there is an increased risk of SSIs in RA patients who use or have recently used TNFis at the time of elective orthopaedic surgery. Prospective studies to confirm these findings and establish the optimal withhold and restart time of TNFis, in the context of other risk factors for infection in RA patients such as higher disease activity, corticosteroid use, smoking and diabetes, are needed.

publication date

  • March 2016

Research

keywords

  • Review

Identity

Language

  • eng

PubMed Central ID

  • PMC5009446

Digital Object Identifier (DOI)

  • 10.1093/rheumatology/kev364

PubMed ID

  • 26447162

Additional Document Info

start page

  • 573

end page

  • 82

volume

  • 55

number

  • 3