Cystoscopy and intravesical bacille Calmette-Guérin therapy in antibiotic-naïve patients with bladder cancer with asymptomatic bacteriuria: An update Review uri icon


MeSH Major

  • Ambulatory Care
  • Urinary Bladder Neoplasms


  • Urologists often insist on sterile urine before invasive outpatient urological procedures, and urine culture and antibiotics are usually given before cystoscopy or instillation of bacille Calmette-Guérin (BCG) therapy, especially in patients who have positive urine cultures. Our experience suggests that cystoscopy and induction BCG therapy can be performed safely, even in patients with asymptomatic bacteriuria, without pretreatment or prophylactic antibiotics. The rate of subsequent febrile urinary tract infection is <4% in both infected and uninfected patients. Pretreatment antibacterial therapy does not appear to be necessary before these two outpatient urological procedures in patients with bladder cancer. Such strategy facilitates timely interventions and reduces the possibility of antibiotic resistance.

publication date

  • June 2016



  • Review



  • eng

PubMed Central ID

  • PMC4963162

Digital Object Identifier (DOI)

  • 10.1016/j.aju.2016.03.002

PubMed ID

  • 27489733

Additional Document Info

start page

  • 75

end page

  • 7


  • 14


  • 2