VEGF-B Improves Metabolic Health through Vascular Pruning of Fat
Vascular Endothelial Growth Factor B
Vascular Endothelial Growth Factor Receptor-2
Unraveling the mechanism VEGF-receptors modulating metabolism has therapeutic implications. In this issue, Robciuc et al. (2016) demonstrate that VEGF-B, by displacing VEGF-A from VEGFR1 and activating VEGFR2, increases adipose tissue vascularity, improves insulin sensitivity, diminishes obesity, and alleviates metabolic syndrome.