Outcome of genetic evaluation of patients with kidney cancer referred for suspected hereditary cancer syndromes Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Renal Cell
  • Colorectal Neoplasms, Hereditary Nonpolyposis
  • Kidney Neoplasms
  • Neoplastic Syndromes, Hereditary

abstract

  • The discovery of inherited kidney cancer syndromes has provided a unique opportunity to identify patients at increased risk for cancer. Factors associated with positive genetic testing are unique to different syndromes. These data suggest that in kidney cancer patients evaluated for hereditary cancer syndromes, young age is associated with diagnosis of RCC syndromes, whereas syndromic manifestations and multiple primaries are found in Lynch syndrome. These results, along with clinical awareness, may be useful for practicing urologists to select patients with kidney cancer to refer for genetic counseling.

publication date

  • May 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4996267

Digital Object Identifier (DOI)

  • 10.1016/j.urolonc.2015.11.021

PubMed ID

  • 26723226

Additional Document Info

start page

  • 238.e1

end page

  • 7

volume

  • 34

number

  • 5