HER2 amplification and her2 mutation are distinct molecular targets in lung cancers Academic Article uri icon

Overview

MeSH Major

  • Adenocarcinoma
  • Genes, erbB-2
  • Lung Neoplasms
  • Mutation

abstract

  • HER2 mutations are not associated with HER2 amplification, thus suggesting a distinct entity and therapeutic target. HER2-positive lung cancer may not be an adequate term, and patient cohorts for the study of HER2-targeted agents should be defined by the specific HER2 alteration present.

publication date

  • March 23, 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4698879

Digital Object Identifier (DOI)

  • 10.1016/j.jtho.2015.10.025

PubMed ID

  • 26723242

Additional Document Info

start page

  • 414

end page

  • 9

volume

  • 11

number

  • 3