Reduced lower-limb muscle strength and volume in patients with type 2 diabetes in relation to neuropathy, intramuscular fat, and Vitamin D levels Academic Article uri icon

Overview

MeSH Major

  • Adiposity
  • Diabetes Mellitus, Type 2
  • Diabetic Neuropathies
  • Muscle Strength
  • Vitamin D Deficiency

abstract

  • Patients with T2DM have a significant reduction in proximal and distal leg muscle strength and a proximal but not distal reduction in muscle volume possibly due to greater intramuscular fat accumulation in distal muscles. Proximal but not distal muscle strength is related to the severity of peripheral neuropathy but not IMNCT or 25OHD level.

publication date

  • March 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC5317239

Digital Object Identifier (DOI)

  • 10.2337/dc15-0995

PubMed ID

  • 26740641

Additional Document Info

start page

  • 441

end page

  • 7

volume

  • 39

number

  • 3