Overall Survival Endpoint in Oncology Clinical Trials: Addressing the Effect of Crossover-The Case of Pazopanib in Advanced Renal Cell Carcinoma Academic Article uri icon

Overview

MeSH Major

  • Angiogenesis Inhibitors
  • Carcinoma, Renal Cell
  • Cross-Over Studies
  • Indoles
  • Kidney Neoplasms
  • Pyrimidines
  • Pyrroles
  • Sulfonamides

abstract

  • This case study supports the need to adjust for confounded OS due to crossover, which enables trials to meet ethical standards and provides decision makers with a more accurate estimate of treatment benefit.

publication date

  • March 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1159/000443647

PubMed ID

  • 26901053

Additional Document Info

start page

  • 119

end page

  • 26

volume

  • 90

number

  • 3