Profilometry: A new statistical framework for the characterization of white matter pathways, with application to multiple sclerosis
Diffusion Magnetic Resonance Imaging
While progress has been made in both tract-profiling and metrics for white matter characterization, no single framework for a joint analysis of multimodality tract profiles accounting for age and gender is known to exist. The profilometry analysis and visualization appears to be a promising method to compare groups using a single score from MANCOVA while assessing the contribution of each metric with LDA. Hum Brain Mapp 37:989-1004, 2016. © 2015 Wiley Periodicals, Inc.
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