Caenorhabditis elegans as a model to study sphingolipid signaling Review uri icon

Overview

MeSH Major

  • Caenorhabditis elegans
  • Sphingolipids

abstract

  • Sphingolipid signaling in Caenorhabditis elegans is vital for sensing environmental change and effecting appropriate cellular response. Many molecular components in sphingolipid intermediary metabolism are conserved throughout evolution. Here we review use of C. elegans as a model system for conducting sphingolipid-based scientific investigation, which has helped us better understand vital roles these remarkable lipids play in human metabolism and disease.

publication date

  • January 2015

Research

keywords

  • Review

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1515/hsz-2014-0298

PubMed ID

  • 25720116

Additional Document Info

start page

  • 767

end page

  • 73

volume

  • 396

number

  • 6-7