Treatment of ulcerative proctitis
© Springer Science+Business Media New York 2014. Ulcerative proctitis is a subset of ulcerative colitis confined to the distal 15–20 cm from the anal verge. The unique quality of inflammation limited to the rectum can often manifest as a challenging disease to effectively treat. The mainstay of medical therapy is topical 5-ASA medicines, usually in the form of suppositories. Oral 5-ASAs are also used, while dual therapy with both has been shown to be most effective. Topical steroids are used to help induce remission but are not appropriate long-term options. Proctitis which is refractory to 5-ASA therapy often requires quick escalation to treatment with biologic agents.
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