Treatment of ulcerative proctitis Chapter uri icon


MeSH Major

  • Anti-Inflammatory Agents
  • Colitis, Ulcerative
  • Crohn Disease


  • © Springer Science+Business Media New York 2014. Ulcerative proctitis is a subset of ulcerative colitis confined to the distal 15–20 cm from the anal verge. The unique quality of inflammation limited to the rectum can often manifest as a challenging disease to effectively treat. The mainstay of medical therapy is topical 5-ASA medicines, usually in the form of suppositories. Oral 5-ASAs are also used, while dual therapy with both has been shown to be most effective. Topical steroids are used to help induce remission but are not appropriate long-term options. Proctitis which is refractory to 5-ASA therapy often requires quick escalation to treatment with biologic agents.

publication date

  • January 2014



  • Book Chapter


Digital Object Identifier (DOI)

  • 10.1007/978-1-4939-1677-1_21

Additional Document Info

start page

  • 251

end page

  • 254