Silk-elastin-like protein polymer matrix for intraoperative delivery of an oncolytic vaccinia virus Academic Article uri icon

Overview

MeSH Major

  • Oncolytic Virotherapy
  • Oncolytic Viruses
  • Thyroid Neoplasms
  • Vaccinia virus

abstract

  • The use of SELP matrix for intraoperative oncolytic viral delivery protects infectious viral particles from degradation, facilitates sustained viral delivery and transgene expression, and improves tumor control. Such optimization of methods of oncolytic viral delivery may enhance therapeutic outcomes.

publication date

  • January 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4975925

Digital Object Identifier (DOI)

  • 10.1002/hed.23877

PubMed ID

  • 25244076

Additional Document Info

start page

  • 237

end page

  • 46

volume

  • 38

number

  • 2