Heterogeneity of lower airway inflammation in children with severe-persistent asthma Academic Article uri icon

Overview

MeSH Major

  • Asthma
  • Bronchoalveolar Lavage Fluid
  • Eosinophils
  • Granulocytes
  • Inflammation
  • Neutrophils

abstract

  • To our knowledge, ours is one of few studies to systematically investigate the pattern of lower airway inflammation in children with severe-persistent asthma. Our results differ from a recent investigation in children, showing more heterogeneity and a greater proportion of neutrophilic inflammation. Further investigation is required to determine whether specific inflammatory patterns are associated with specific etiologies, and whether individualized therapy is warranted.

publication date

  • December 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/ppul.23165

PubMed ID

  • 25739748

Additional Document Info

start page

  • 1200

end page

  • 4

volume

  • 50

number

  • 12