Microenvironmental hCAP-18/LL-37 promotes pancreatic ductal adenocarcinoma by activating its cancer stem cell compartment Academic Article uri icon

Overview

MeSH Major

  • Antimicrobial Cationic Peptides
  • Carcinoma, Pancreatic Ductal
  • Neoplastic Stem Cells
  • Pancreatic Neoplasms
  • Tumor Microenvironment

abstract

  • Thus, hCAP-18/LL-37 represents a previously unrecognised PDAC microenvironment factor that plays a critical role in pancreatic CSC-mediated tumourigenesis.

publication date

  • December 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1136/gutjnl-2014-308935

PubMed ID

  • 25841238

Additional Document Info

start page

  • 1921

end page

  • 35

volume

  • 64

number

  • 12