Critical roles of STAT3 in β-adrenergic functions in the heart
Receptors, Adrenergic, beta
STAT3 Transcription Factor
Our data demonstrate for the first time that STAT3 has a fundamental role in βAR signaling and functions in the heart. STAT3 serves as a critical transcriptional regulator for βAR-mediated cardiac stress adaption, pathological remodeling, and heart failure.