Critical roles of STAT3 in β-adrenergic functions in the heart Academic Article uri icon

Overview

MeSH Major

  • Heart
  • Receptors, Adrenergic, beta
  • STAT3 Transcription Factor

abstract

  • Our data demonstrate for the first time that STAT3 has a fundamental role in βAR signaling and functions in the heart. STAT3 serves as a critical transcriptional regulator for βAR-mediated cardiac stress adaption, pathological remodeling, and heart failure.

publication date

  • January 5, 2016

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4698100

Digital Object Identifier (DOI)

  • 10.1161/CIRCULATIONAHA.115.017472

PubMed ID

  • 26628621

Additional Document Info

start page

  • 48

end page

  • 61

volume

  • 133

number

  • 1