TOLLIP, MUC5B, and the response to N-acetylcysteine among individuals with idiopathic pulmonary fibrosis Academic Article uri icon

Overview

MeSH Major

  • Huntington Disease
  • Lipid Peroxidation
  • Mitochondria
  • Neostriatum

abstract

  • NAC may be an efficacious therapy for individuals with IPF with an rs3750920 (TOLLIP) TT genotype, but it was associated with a trend toward harm in those with a CC genotype. A genotype-stratified prospective clinical trial should be conducted before any recommendation regarding the use of off-label NAC to treat IPF.

publication date

  • December 15, 2015

Research

keywords

  • Academic Article

Additional Document Info

start page

  • 1475

end page

  • 82

volume

  • 192

number

  • 12