Severe nephrotoxic nephritis following conditional and kidney-specific knockdown of stanniocalcin-1 Academic Article uri icon

Overview

MeSH Major

  • Glycoproteins
  • Kidney
  • Nephritis

abstract

  • nephrotoxic nephritis after kidney-specific knockdown of STC1 is characterized by severe tubular and glomerular necrosis, possibly due to loss of STC1-mediated pro-survival factors, and we attribute the paucity of inflammation to diminished release of cytokines/chemokines/growth factors from the necrotic epithelium.

publication date

  • September 22, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4579070

Digital Object Identifier (DOI)

  • 10.1371/journal.pone.0138440

PubMed ID

  • 26393521

Additional Document Info

start page

  • e0138440

volume

  • 10

number

  • 9