Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans Academic Article uri icon

Overview

MeSH Major

  • African Americans
  • European Continental Ancestry Group
  • Inflammatory Bowel Diseases
  • Polymorphism, Single Nucleotide

abstract

  • In a genetic analysis of 3308 AA IBD cases and controls, we found that many variants associated with IBD in Caucasians also showed association evidence with these diseases in AAs; we also found evidence for variants and loci not previously associated with IBD. The complex genetic factors that determine risk for or protection against IBD in different populations require further study.

authors

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4685036

Digital Object Identifier (DOI)

  • 10.1053/j.gastro.2015.07.065

PubMed ID

  • 26278503

Additional Document Info

start page

  • 1575

end page

  • 86

volume

  • 149

number

  • 6