Non-invasive PET Imaging of PARP1 Expression in Glioblastoma Models Academic Article uri icon

Overview

MeSH Major

  • Brain Neoplasms
  • Glioblastoma
  • Poly(ADP-ribose) Polymerases
  • Positron-Emission Tomography

abstract

  • [(18)F]PARPi is a selective PARP1 imaging agent that can be used to visualize glioblastoma in xenograft and orthotopic mouse models with high precision and good signal/noise ratios. It offers new opportunities to non-invasively image tumor growth and monitor interventions.

publication date

  • October 22, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4841747

Digital Object Identifier (DOI)

  • 10.1007/s11307-015-0904-y

PubMed ID

  • 26493053

Additional Document Info