The Role of I-123 Metaiodobenzylguanidine Imaging in Management of Patients with Heart Failure Academic Article uri icon


MeSH Major

  • 3-Iodobenzylguanidine
  • Arrhythmias, Cardiac
  • Death, Sudden, Cardiac
  • Heart
  • Heart Failure
  • Radiopharmaceuticals
  • Sympathetic Nervous System
  • Ventricular Dysfunction, Left


  • Despite advances in evidence-based treatments, the morbidity and mortality of congestive heart failure remain exceedingly high. In addition, the costs associated with recurrent hospitalizations and advanced therapies, such as implantable cardiac defibrillators (ICDs), left ventricular assist devices, and heart transplantation, place a substantial financial burden on the health care system. The present criteria for risk stratification in patients with heart failure are inadequate and often prevent the allocation of appropriate treatment. Patients who have received ICDs as primary prevention for sudden cardiac death often receive no device therapy in their lifetime, whereas other patients with left ventricular dysfunction die suddenly without meeting criteria for ICD implantation.

publication date

  • January 2015



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.1016/j.amjcard.2015.09.014

PubMed ID

  • 26454812

Additional Document Info

start page

  • S1

end page

  • 9


  • 116