Early recurrence and cerebral bleeding in patients with acute ischemic stroke and atrial fibrillation: Effect of anticoagulation and its timing: The RAF study Academic Article uri icon

Overview

MeSH Major

  • Anticoagulants
  • Atrial Fibrillation
  • Brain Ischemia
  • Cerebral Hemorrhage
  • Stroke

abstract

  • Acute stroke in atrial fibrillation patients is associated with high rates of ischemic recurrence and major bleeding at 90 days. This study has observed that high CHA2DS2-VASc score, high National Institutes of Health Stroke Scale, large ischemic lesions, and type of anticoagulant administered each independently led to a greater risk of recurrence and bleedings. Also, data showed that the best time for initiating anticoagulation treatment for secondary stroke prevention is 4 to 14 days from stroke onset. Moreover, patients treated with oral anticoagulants alone had better outcomes compared with patients treated with low molecular weight heparins alone or before oral anticoagulants.

authors

publication date

  • August 30, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1161/STROKEAHA.115.008891

PubMed ID

  • 26130094

Additional Document Info

start page

  • 2175

end page

  • 82

volume

  • 46

number

  • 8