Prediction of quality of life and survival after surgery for symptomatic spinal metastases: A multicenter cohort study to determine suitability for surgical treatment Academic Article uri icon


MeSH Major

  • Preoperative Care
  • Quality of Life
  • Spinal Neoplasms


  • Data from the largest prospective surgical series of patients with symptomatic spinal metastases revealed that tumor type, the number of spinal metastases, and the presence of visceral metastases are the most useful predictors of survival and that quality of life is best predicted by preoperative Karnofsky, Frankel, and EQ-5D scores. The Karnofsky score predicts quality of life and survival and is easy to determine at the bedside, unlike the EQ-5D index. Karnofsky score, tumor type, and spinal and visceral metastases should be considered the 4 most important prognostic variables that influence patient management.

publication date

  • January 2015



  • Academic Article



  • eng

Digital Object Identifier (DOI)

  • 10.1227/NEU.0000000000000907

PubMed ID

  • 26204361

Additional Document Info

start page

  • 698

end page

  • 708; discussion 708


  • 77


  • 5