Non-16/18 high-risk HPV infection predicts disease persistence and progression in women with an initial interpretation of LSIL Academic Article uri icon

Overview

MeSH Major

  • Carcinoma, Squamous Cell
  • Cervical Intraepithelial Neoplasia
  • DNA, Viral
  • Papillomavirus Infections

abstract

  • Infection with non-16/18 HR-HPV genotypes but not with HPV-16/18 genotypes was a strong predictor of the persistence and progression of cervical disease upon follow-up. Genotyping solely for HPV-16/18 would miss the majority of patients with LSIL who progress to high-grade squamous intraepithelial lesions. Pooled HR-HPV tests provide a better predictive value than HPV-16/18 genotyping alone in guiding the clinical management of patients with LSIL.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1002/cncy.21549

PubMed ID

  • 25903015

Additional Document Info

start page

  • 435

end page

  • 42

volume

  • 123

number

  • 7