The role of nitric oxide synthase uncoupling in tumor progression Academic Article uri icon

Overview

MeSH Major

  • Disease Progression
  • Neoplasms
  • Nitric Oxide Synthase

abstract

  • The synthetic BH4, Kuvan, is used to elevate BH4:BH2 in some phenylketonuria patients and to treat diseases associated with endothelial dysfunction, suggesting a novel, testable approach for correcting an abnormality of tumor metabolism to control tumor growth.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4470720

Digital Object Identifier (DOI)

  • 10.1158/1541-7786.MCR-15-0057-T

PubMed ID

  • 25724429

Additional Document Info

start page

  • 1034

end page

  • 43

volume

  • 13

number

  • 6