Inhibition of CD47 Effectively targets pancreatic cancer stem cells via dual mechanisms Academic Article uri icon

Overview

MeSH Major

  • Antibodies, Monoclonal, Murine-Derived
  • Antineoplastic Agents
  • CD47 Antigen
  • Carcinoma, Pancreatic Ductal
  • Neoplastic Stem Cells
  • Pancreatic Neoplasms

abstract

  • These data are consistent with efficient in vivo targeting of CSCs, and strongly suggest that CD47 inhibition could be a novel adjuvant treatment strategy for PDAC independent of underlying and highly variable driver mutations.

publication date

  • May 15, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1158/1078-0432.CCR-14-1399

PubMed ID

  • 25717063

Additional Document Info

start page

  • 2325

end page

  • 37

volume

  • 21

number

  • 10