Targeted Prostate Biopsy: Lessons Learned Midst the Evolution of a Disruptive Technology Review uri icon


MeSH Major

  • Image-Guided Biopsy
  • Magnetic Resonance Imaging
  • Prostatic Neoplasms


  • Lessons learned during a 6-year experience with more than 1200 patients undergoing targeted prostate biopsy via MRI/ultrasound fusion are reported: (1) the procedure is safe and efficient, requiring some 15-20 minutes in an office setting; (2) MRI is best performed by a radiologist with specialized training, using a transabdominal multiparametric approach and preferably a 3T magnet; (3) grade of MRI suspicion is the most powerful predictor of biopsy results, eg, Grade 5 usually represents cancer; (4) some potentially important cancers (15%-30%) are MRI-invisible; (5) Targeted biopsies provide >80% concordance with whole-organ pathology. Early enthusiasm notwithstanding, cost-effectiveness is yet to be resolved, and the technologies remain in evolution.

publication date

  • September 2015



  • Review



  • eng

PubMed Central ID

  • PMC4569505

Digital Object Identifier (DOI)

  • 10.1016/j.urology.2015.07.001

PubMed ID

  • 26166671

Additional Document Info

start page

  • 432

end page

  • 8


  • 86


  • 3