Radioiodinated PARP1 tracers for glioblastoma imaging Academic Article uri icon

Overview

MeSH Major

  • Fusion Proteins, bcr-abl
  • Piperazines
  • Pyrimidines

abstract

  • We have successfully synthesized and radioiodinated the PARP1 selective tracer I2-PARPi. The novel tracer shows selective binding to tumor tissue, both in vitro and in models of glioblastoma, and has the potential to serve as a selective PET imaging agent for brain tumors.

publication date

  • December 8, 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

PubMed Central ID

  • PMC4559561

Digital Object Identifier (DOI)

  • 10.1186/s13550-015-0123-1

PubMed ID

  • 26337803

Additional Document Info

start page

  • 123

volume

  • 5

number

  • 1