Clinical characteristics of uveal melanoma in patients with germline BAP1 mutations Academic Article uri icon

Overview

MeSH Major

  • Germ-Line Mutation
  • Melanoma
  • Polymorphism, Single Nucleotide
  • Tumor Suppressor Proteins
  • Ubiquitin Thiolesterase
  • Uveal Neoplasms

abstract

  • These data suggest that germline BAP1 mutations occur infrequently in uveal melanoma and are associated with larger tumors and higher rates of ciliary body involvement, 2 known risk factors for metastasis.

publication date

  • January 2015

Research

keywords

  • Academic Article

Identity

Language

  • eng

Digital Object Identifier (DOI)

  • 10.1001/jamaophthalmol.2015.1119

PubMed ID

  • 25974357

Additional Document Info

start page

  • 881

end page

  • 7

volume

  • 133

number

  • 8